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Cranberries: scientific studies*

 

Scientific studies show that cranberries anthocyanins have many health benefits, including:

  • protecting against bacterial infections in the urinary system and preventing bacterias from seizing into bladder walls (1-6)

  • preventing the formation of alkaline stones in the urinary tract by working against bacterial-infections

  • preventing the development of cavities in teeth in a way similar to the action in preventing urinary tract infections

  • fighting oxydative stress (7)

  • displaying anti-proliferative activity against several types of cancer in vitro and in vivo, including gastric cancer (8) and esophageal adenocarcinoma. (9) 

  • fending off ulcers by preventing helicobacter pylori, the bacterium which causes peptic ulcers, from adhering to the stomach lining. (10,11)

  • lowering bad cholesterol levels and increasing good cholesterol levels in the blood.

1. Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. Di Martino P, World J Urol. 2006 Feb;24(1):21-7. Epub 2006 Jan 6

http://www.ncbi.nlm.nih.gov/pubmed/16397814?dopt=AbstractPlus

2. Do cranberries help prevent urinary tract infections? Hutchinson J., Nurs Times. 2005 Nov 22-28;101(47):38-40.

http://www.ncbi.nlm.nih.gov/pubmed/16329274?dopt=Abstract

3. Cranberries for preventing urinary tract infections. Jepson R, Mihaljevic L, Craig J. 

Cochrane Database Syst Rev. 2004;1:CD001321.

http://www.ncbi.nlm.nih.gov/pubmed/14973968?dopt=abstract

4. Characterization of flavonols in cranberry (Vaccinium macrocarpon) powder.

Vvedenskaya IO, Rosen RT, Guido JE, Russell DJ, Mills KA, Vorsa N.

J Agric Food Chem. 2004 Jan 28;52(2):188-95.                                                                                                                                       http://www.ncbi.nlm.nih.gov/pubmed/14733493?dopt=abstract

5. The role of cranberry juice in the treatment of urinary tract infections.

Griffiths P. Br J Community Nurs. 2003 Dec;8(12):557-61.

http://www.ncbi.nlm.nih.gov/pubmed/14688663?dopt=abstract

6. Cranberry juice consumption may reduce biofilms on uroepithelial cells: pilot study in spinal cord injured patients. 

Reid G, Hsiehl J, Potter P, Mighton J, Lam D, Warren D, Stephenson J. 

Spinal Cord 2001 Jan;39(1):26-30

http://www.ncbi.nlm.nih.gov/pubmed/11224011?dopt=abstract

7. Valentova K, Stejskal D, Bednar P, et al. Biosafety, antioxidant status and metabolites in urine after consumption of dried cranberry juice in healthy women: a pilot double-blind placebo-controlled trial. J Agric Food Chem. 2007 Apr 18;55:3217-24.

8. Liu M, Lin LQ, Song BB, et al. Cranberry phytochemical extract inhibits SGC-7901 cell growth and human tumor xenografts in Balb/c nu/nu mice. J Agric Food Chem. 2009 Jan 28;57(2):762-8.

9. Kresty LA, Howell AB, Baird M. Cranberry proanthocyanidins induce apoptosis and inhibit acid-induced proliferation of human esophageal adenocarcinoma cells. J Agric Food Chem. 2008 Feb 13;56(3):676-80.

10. Zhang L, Ma J, Pan K, Go VL, Chen J, You WC. Efficacy of cranberry juice on Helicobacter pylori infection: a double-blind, randomized placebo-controlled trial. Helicobacter. 2005 Apr;10(2):139-45.

11.Burger O, Weiss E, Sharon N, Tabak M, Neeman I, Ofek I. Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice. Crit Rev Food Sci Nutr. 2002;42(3 Suppl):279-84.

*Through this site we are only furthering scientific results; on no account we supply medical advices.

The content of this website has not been verified by a physician.

 

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